thieno[2,3-c]furan-4,6-dione → 3-(2-Methylbenzoyl)-2-thiophenecarboxylic acid

HRID 1081334노트

반응식

HRID 1081334 반응식
[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:8][C:9](=[O:10])[C:2]1=2)=[O:7].[CH3:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[Mg]Br>C1COCC1>[CH3:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:6]([C:3]1[CH:4]=[CH:5][S:1][C:2]=1[C:9]([OH:8])=[O:10])=[O:7]

참가 물질

4

반응물 2

HCID 222951thieno[2,3-c]furan-4,6-dioneHCID 178424303HCID 178424303, 화합물

생성물 1

HCID 233640543-(2-Methylbenzoyl)-2-thiophenecarboxylic acid

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2,3-Thiophenedicarboxylic anhydride was allowed to react with 2-methylphenyl magnesium bromide in THF, and the reaction mixture was processed to give 3-(2-methylbenzoyl)-2-thiophenecarboxylic acid as colorless crystals.

출처 및 근거

ORD 기록
ord-b3fd19d962724aeda8e7836ae374750a
출처 데이터셋
uspto-grants-1996_12
특허 번호
US05585385

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