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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 10816생성일: 2026년 10월 23일

Cyanamide → {4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-methoxy-phenyl)-methanone

https://huagongshe.com/ko/reaction/10816

반응식

참여 물질

역할이름HCID투입량
반응물CyanamideHCID 9864—
반응물Bromomethyl 3-methoxyphenyl ketoneHCID 101294—
반응물1-(4-Isothiocyanatophenyl)-4-cyclopropylmethylpiperazineHCID 21958916—
생성물{4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-methoxy-phenyl)-methanoneHCID 21958932—

반응 단계

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-1-(3-methoxyphenyl)ethanone (Aldrich) following the procedure used in Example 24 Mass spectrum (ES) MH+=464.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07094896B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-85ee76f1be514947a55c08761ca008f0
출처 메모uspto-grants-2006_08