참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Isophthalaldehyde | HCID 34777 | — |
| 반응물 | 2-Methyl-6-phenylpyridine | HCID 2762885 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 생성물 | 3-(2-(6-Phenylpyridin-2-yl)ethenyl)benzaldehyde | HCID 53953962 | — |
반응 단계
A mixture of 2-methyl-6-phenylpyridine (525 mg) (step 2), isophthalaldehyde (630 mg) and dry zinc chloride (40 mg) was heated at 160° C. under N2 for 3 hours. The resulting mixture was partitioned between 25% aqueous NH40Ac (20 cc) and ethyl acetate (20 cc) The organic layer was washed with H2O (10 cc), brine and solvent as removed in vacuo. The residue was purified by chromatography to afford the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05004743 |
|---|
| 출처 데이터셋 | uspto-grants-1991_04 |
|---|
| ORD ID | ord-f283381da93346dab8a20399803753e3 |
|---|
| 출처 메모 | uspto-grants-1991_04 |
|---|
