Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Dimethyl 3-(4-methoxycarbonylphenyl)-2-isoxazolin-5-ylphosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | Dimethyl vinylphosphonate | HCID 78376 | — |
| 반응물 | Methyl 4-(hydroxyamino)benzoate | HCID 11137507 | — |
| 생성물 | Dimethyl 3-(4-methoxycarbonylphenyl)-2-isoxazolin-5-ylphosphonate | HCID 14460581 | — |
반응 단계
Reaction of 80.6 g (0.45 mol) of methyl 4-hydroxyaminobenzoate, 67.0 g (0.5 mol) of N-chlorosuccinimide, 61.25 g (0.45 mol) of dimethyl vinylphosphonate and 78.45 ml (0.56 mol) of triethylamine as in Example 1 provides, after recrystallization from tert.butyl methyl ether, 115.2 g of pure product of melting point 93° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05006515 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-02d9460b3412401a8a35929ddf9a6867 |
| 출처 메모 | uspto-grants-1991_04 |