3,5-Dimethylbenzoyl Chloride → HCID 14366285, 화합물

HRID 1085364노트

반응식

HRID 1085364 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5](Cl)=[O:6].C[O:13][P:14]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1>CC(C)=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5]([P:14]1(=[O:13])[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1)=[O:6]

참가 물질

4

반응물 2

HCID 810883,5-Dimethylbenzoyl ChlorideHCID 114361486-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin

생성물 1

HCID 14366285HCID 14366285, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

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온도
115 °C

실험 절차

67.4 g (0.4 mol) of 3,5-dimethylbenzoyl chloride were warmed to 80° C. under a nitrogen atmosphere. 92 g (0.4 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. The temperature during the addition was increased in steps to 115° C. When the reaction was complete, 50 ml of acetone were added at room temperature. After crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C. were obtained.

후처리

  1. additionThe temperature during the addition
  2. customAfter crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C.
  3. customwere obtained

출처 및 근거

ORD 기록
ord-909d4e16ecf84701bb764513ffb2bc94
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05008426

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