2-(2,4-Dichlorophenoxy)propanoyl chloride → HCID 18633419, 화합물

HRID 1085522노트

반응식

HRID 1085522 반응식
[Cl:1][C:2]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:3]=1[O:4][CH:5]([CH3:9])[C:6](Cl)=[O:7].[NH2:15][CH2:16][C@H:17]1[O:21][C@@H:20]([N:22]2[CH:29]=[C:28]([CH2:30][CH3:31])[C:26](=[O:27])[NH:25][C:23]2=[O:24])[CH2:19][C@@H:18]1[O:32][CH2:33][CH3:34]>>[Cl:1][C:2]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:3]=1[O:4][CH:5]([CH3:9])[C:6]([NH:15][CH2:16][C@H:17]1[O:21][C@@H:20]([N:22]2[CH:29]=[C:28]([CH2:30][CH3:31])[C:26](=[O:27])[NH:25][C:23]2=[O:24])[CH2:19][C@@H:18]1[O:32][CH2:33][CH3:34])=[O:7]

참가 물질

3

반응물 2

HCID 143033802-(2,4-Dichlorophenoxy)propanoyl chlorideHCID 186334585'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine

생성물 1

HCID 18633419HCID 18633419, 화합물

실험 절차

In an analogous manner, from 2(RS)-(2,4-dichlorophenoxy)propionyl chloride (prepared from the acid) and 5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine, there was obtained 5'-[2(RS)-(2,4 -dichlorophenoxy)propionamido]-2',5'-dideoxy-3'O-ethyl-5-ethyluridine of melting point 121°-124° C.

출처 및 근거

ORD 기록
ord-a6532acda1d34b068ab10023e3045faa
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05010060

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