Guanidine Hydrochloride → HCID 14718745, 화합물
반응식
C[O-].[Na+].Cl.[NH2:5][C:6]([NH2:8])=[NH:7].CN(C)[CH:11]=[C:12]([CH:22]=O)[CH:13]([CH:19]([CH3:21])[CH3:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15]>C(O)C>[NH2:7][C:6]1[N:8]=[CH:11][C:12]([CH:13]([CH:19]([CH3:20])[CH3:21])[C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:22][N:5]=1참가 물질
5
실험 절차
A solution of sodium methoxide (0.9 g) in ethanol (5 cm3) was added dropwise to a stirred suspension of guanidine hydrochloride (1.58 g) and ethyl (RS)-4-dimethylamino-3-formyl-2-(1-methylethyl)-3-butenoate in ethanol (10 cm3). The reaction mixture was heated at the reflux temperature for 2 hours, then stood at the ambient temperature for 70 hours. The solvent was evaporated under reduced pressure and water added to the residue.
후처리
- temperatureThe reaction mixture was heated at the reflux temperature for 2 hours
- customThe solvent was evaporated under reduced pressure and water
- additionadded to the residue
출처 및 근거
- ORD 기록
- ord-6790dc93d638455f936ed00efb37a162
- 출처 데이터셋
- uspto-grants-1991_04
- 특허 번호
- US05010200
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