Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 5-phenyl-1,3-thiazole-4-carboxylic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl 5-phenylthiazole-4-carboxylate | HCID 12300673 | — |
| 생성물 | 5-phenyl-1,3-thiazole-4-carboxylic Acid | HCID 944813 | 72% |
반응 단계
The ethyl 5-phenylthiazole-4-carboxylate was hydrolyzed according to known methods with 2N aqueous sodium hydroxide solution at 70° for 30 minutes, whereby, after acidification, there was obtained in 72% yield 5-phenyl-4-thiazolecarboxylic acid which melted at 189°-190° after recrystallization from methanol/diethyl ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05011849 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-1117adfa47b24e9487183e996d0fdc8a |
| 출처 메모 | uspto-grants-1991_04 |