Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 3-Trifluoromethylbenzoic acid [1-(3-pyridinyl)propylidene]hydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 1-(3-Pyridyl)propan-1-one | HCID 74074 | — |
| 반응물 | 3-(Trifluoromethyl)benzoic acid hydrazide | HCID 2777417 | — |
| 촉매 | Acetic Acid | HCID 176 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Trifluoromethylbenzoic acid [1-(3-pyridinyl)propylidene]hydrazide | HCID 54045504 | 74% |
반응 단계
A mixture of 10.21 gm (0.05 mole) of 3-trifluoromethylbenzoic acid hydrazide, 6.76 gm (0.05 mole) of ethyl-3-pyridyl ketone, 10 drops of glacial acetic acid and 100 ml of absolute ethanol was refluxed 15 hr. The reaction mixture was diluted with water to the cloud point and cooled to room temperature then chilled in the refrigerator. The solids that separated were collected, washed with Skellysolve B and dried to give 11.88 gm (74%) of product having a melting point of 119.4° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05011932 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-2b4e538ebdce439b8fa05d5427632b7c |
| 출처 메모 | uspto-grants-1991_04 |