Diethylamine → HCID 178455924, 화합물

HRID 1086126노트

반응식

HRID 1086126 반응식
C(NCC)C.[NH:6](C(OCC1C2C(=CC=CC=2)C2C1=CC=CC=2)=O)[C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:21])[NH2:20])=[O:12])[CH:8]([CH3:10])[CH3:9]>CN(C)C=O>[NH2:6][C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:20])[NH2:21])=[O:12])[CH:8]([CH3:10])[CH3:9]

참가 물질

4

반응물 2

HCID 8021DiethylamineHCID 178455925HCID 178455925, 화합물

생성물 1

HCID 178455924HCID 178455924, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

31.5 ml of diethylamine are added to a solution of 21 g (30 mmol) of Fmoc-Val-Arg-Ile-OBzl in 200 ml of dimethylformamide. The mixture is left to stand at room temperature for 10 minutes, and is concentrated in vacuo. The residue is triturated with diethyl ether and filtered off with suction.

후처리

  1. waitThe mixture is left
  2. concentrationis concentrated in vacuo
  3. customThe residue is triturated with diethyl ether
  4. filtrationfiltered off with suction

출처 및 근거

ORD 기록
ord-13a7e8668c1f49ed8ccba1ad01d60636
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05011825

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