Ethyl Dodecanoate → 1-(2-Hydroxyethyl)-2-undecylimidazoline

HRID 1086434

반응식

HRID 1086434 반응식
[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][OH:7].[C:8](OCC)(=O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[OH:7][CH2:6][CH2:5][N:4]1[CH2:3][CH2:2][N:1]=[C:19]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH3:8]

참가 물질

3

반응물 2

HCID 7800Ethyl DodecanoateHCID 8112N-(2-Hydroxyethyl)ethylenediamine

생성물 1

HCID 87091-(2-Hydroxyethyl)-2-undecylimidazoline수율 69.5%

실험 절차

58.7 g (564.4 mmoles) of 2-(2-aminoethylamino)ethanol and 122.8 g (538.6 mmoles) of ethyl dodecanoate were heated at 125° C. and ethanol was removed by distillation. 100 ml of toluene was cautiously added and water was removed azeotropically on further reflux. The reaction mixture was fractionally distilled to give 100.2 g (69.5%) of pure product, m.p. 40°-42° C.

후처리

  1. customethanol was removed by distillation
  2. addition100 ml of toluene was cautiously added
  3. customwater was removed azeotropically on further reflux
  4. distillationThe reaction mixture was fractionally distilled

출처 및 근거

ORD 기록
ord-9a32d83b4e084061b5532e0c93cbc024
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05030629

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