Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Isobenzofurandione, 5-fluoro- → Ethyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Isobenzofurandione, 5-fluoro- | HCID 67572 | — |
| 반응물 | Ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982228 | — |
| 생성물 | Ethyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982246 | — |
반응 단계
Ethyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.77 g, 56%) in the same manner as described in the above example 5 (20) from ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.80 g, 3.94 mmol) and 4-fluorophthalic anhydride (0.78 g, 4.72 mmol), and the obtained product was identified with the following NMR data.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094908B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-06ae0656ad3549c789a8f7bfef960b25 |
| 출처 메모 | uspto-grants-2006_08 |