Dimethylamine → Ethyl 3-(N,N-dimethylamino)acrylate
반응식
[CH3:1][NH:2][CH3:3].[CH:4]([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=O.[Na]>C1(C)C=CC=CC=1>[CH3:1][N:2]([CH3:3])[CH:4]=[CH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8]참가 물질
4
반응 조건
- 온도
- 20 °C
실험 절차
13.1 g (0.29 mol) of dimethylamine were introduced into a suspension of 40 g (0.29 mol) of sodium ethyl formylacetate in 50 ml of toluene and 50 ml of ethanol. HCl gas was then introduced until the point of neutrality was reached and the mixture was stirred at 20° C. for 2 h. After filtering off the precipitate with suction, the mixture was worked up in a customary manner. Ethyl β-dimethylaminoacrylate was obtained in a yield of 91.6%.
후처리
- additionwas then introduced until the point of neutrality
- filtrationAfter filtering off the precipitate with suction
출처 및 근거
- ORD 기록
- ord-9078f70fac4248ec96ff214ca2fa8560
- 출처 데이터셋
- uspto-grants-1991_07
- 특허 번호
- US05030747
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