1-Chloroanthraquinone → 1-(n-Octylsulfonylamino)anthraquinone

HRID 1087301

반응식

HRID 1087301 반응식
Cl[C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH2:18]([S:26]([NH2:29])(=[O:28])=[O:27])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].C(=O)([O-])[O-].[K+].[K+]>C([O-])(=O)C.[Cu+2].C([O-])(=O)C.ClC1C=CC=CC=1Cl>[CH2:18]([S:26]([NH:29][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[CH:5]=[CH:4][CH:3]=1)(=[O:27])=[O:28])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

참가 물질

6

반응물 3

HCID 67091-ChloroanthraquinoneHCID 11430Potassium CarbonateHCID 2295971-Octanesulfonamide

생성물 1

HCID 199903611-(n-Octylsulfonylamino)anthraquinone

시약·촉매·용매 2

HCID 8895Cupric acetate촉매HCID 72391,2-Dichlorobenzene용매

실험 절차

A 100ml round bottom flask, equipped with a magnetic stirrer and cooling condenser, was charged with 1-chloroanthraquinone (2.0g), n-octylsulfonamide (3.0g), copper acetate (0.8g), potassium carbonate (0.8g) and o-dichlorobenzene (25ml). This mixture was slowly heated to reflux. After 2.5 hours the reaction mixture was cooled and filtered. Methanol was then added to induce precipitation, and after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product.

후처리

  1. customA 100ml round bottom flask, equipped with a magnetic stirrer
  2. temperaturecooling condenser
  3. temperatureThis mixture was slowly heated to reflux
  4. temperatureAfter 2.5 hours the reaction mixture was cooled
  5. filtrationfiltered
  6. additionMethanol was then added
  7. customprecipitation
  8. filtrationafter filtration the solid
  9. customwas recrystallized from a mixture of dichloromethane and methanol
  10. customto give a yellow product

출처 및 근거

ORD 기록
ord-3e6a13242a364f83931fe3aa4a4de4e3
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05034547

연결된 노트

불러오는 중…