Potassium Carbonate → 1-(n-Octylsulfonylamino)-8-aminoanthraquinone

HRID 1087304

반응식

HRID 1087304 반응식
[NH2:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3Cl)[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][S:27]([NH2:30])(=[O:29])=[O:28].C(=O)([O-])[O-].[K+].[K+]>ClC1C=CC=CC=1>[CH2:26]([S:27]([NH:30][C:12]1[C:13]2[C:14](=[O:16])[C:15]3[C:6](=[CH:5][CH:4]=[CH:3][C:2]=3[NH2:1])[C:7](=[O:18])[C:8]=2[CH:9]=[CH:10][CH:11]=1)(=[O:29])=[O:28])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH3:19]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 2236691-Amino-8-chloroanthraquinoneHCID 2295971-Octanesulfonamide

생성물 1

HCID 198180061-(n-Octylsulfonylamino)-8-aminoanthraquinone

시약·촉매·용매 1

HCID 7964Chlorobenzene용매

실험 절차

1-(n-octylsulfonylamino)-8-aminoanthraquinone was prepared as follows. 1-amino-8-chloroanthraquinone (1.0g), n-octanesulfonamide (1.0g), potassium carbonate (1.0g), cupric acetate monohydrate (0.85g) and chlorobenzene (16.0g) were refluxed for 5.5 hours. The cooled mixture was filtered and aqueous methanol was added to the filtrate. The supernatant liquid was decanted and the remaining oil was dissolved in dichloromethane. On addition of methanol and partial evaporation of the solvent, the product separated as a red solid.

후처리

  1. filtrationThe cooled mixture was filtered
  2. additionaqueous methanol was added to the filtrate
  3. customThe supernatant liquid was decanted
  4. dissolutionthe remaining oil was dissolved in dichloromethane
  5. additionOn addition of methanol and partial evaporation of the solvent
  6. customthe product separated as a red solid

출처 및 근거

ORD 기록
ord-83651583e42e4f30a2ee99efb5716dee
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05034547

연결된 노트

불러오는 중…