1-Propanol → Propyl pyrazinoate

HRID 1088238노트

반응식

HRID 1088238 반응식
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7](Cl)=[O:8].N1C=C[CH:13]=[CH:12][CH:11]=1.C([OH:19])CC>C(Cl)Cl>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]([O:8][CH2:11][CH2:12][CH3:13])=[O:19]

참가 물질

5

반응물 3

HCID 10311-PropanolHCID 1049PyridineHCID 88279Pyrazinecarbonyl chloride

생성물 1

HCID 72507Propyl pyrazinoate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To 4.0 g (28 mmol) of pyrazinoyl chloride dissolved in methylene chloride (20 mL) and pyridine (2 mL) cooled to 0° C. in a 50 mL round bottom flask was added n-propyl alcohol (4.0 g, 66 mmol). Completion of the reaction and separation as described above, followed by distillation, led to isolation of the title compound as a water white oil; b.p: 68°-73° C. at 0.20 mm Hg.

후처리

  1. customCompletion of the reaction and separation
  2. distillationfollowed by distillation

출처 및 근거

ORD 기록
ord-5e35d677b44e4426bd94407fb40b664c
출처 데이터셋
uspto-grants-1990_10
특허 번호
US04962111

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