Methyl p-toluenesulfonate → HCID 86744275, 화합물

HRID 1088577

반응식

HRID 1088577 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][CH2:9][OH:10])[CH:2]=1.[C:11]1([CH3:22])[CH:16]=[CH:15][C:14]([S:17]([O:20]C)(=[O:19])=[O:18])=[CH:13][CH:12]=1>CC(C)=O>[C:11]1([CH3:22])[CH:12]=[CH:13][C:14]([S:17]([O-:20])(=[O:18])=[O:19])=[CH:15][CH:16]=1.[OH:10][CH2:9][CH:8]=[CH:7][C:3]1[CH:2]=[N+:1]([CH3:11])[CH:6]=[CH:5][CH:4]=1

참가 물질

4

반응물 2

HCID 6645Methyl p-toluenesulfonateHCID 35635042-Propen-1-ol, 3-(3-pyridinyl)-

생성물 1

HCID 86744275HCID 86744275, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Ethyl 3-(3-pyridyl)acrylate was reduced using lithium aluminum hydride to give 3-(3-pyridyl)-2-propen-1-ol. In 30 ml of acetone 710 mg of 3-(3-pyridyl)-2-propen-1-ol and 980 mg of methyl p-toluenesulfonate were heated under reflux for 22 hours. The reaction mixture was subjected by decantation to remove the solvent and then washed with acetone and ether. The residue was dried under reduced pressure to give 1.3 g of the desired compound as an orange-colored oil.

후처리

  1. temperatureunder reflux for 22 hours
  2. customto remove the solvent
  3. washwashed with acetone and ether
  4. customThe residue was dried under reduced pressure

출처 및 근거

ORD 기록
ord-ab0bd96f038e4c9a91427c8f4d4a31c1
출처 데이터셋
uspto-grants-1990_10
특허 번호
US04962096

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