Acetophenone → 1-Phenyl-3-(3-methoxy-4-hydroxy-5-trifluoromethylphenyl)prop-2-en-1-one

HRID 1088875노트

반응식

HRID 1088875 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([C:12]([F:15])([F:14])[F:13])[C:10]=1[OH:11])[CH:6]=O.[C:16]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)(=[O:18])[CH3:17]>>[C:19]1([C:16](=[O:18])[CH:17]=[CH:6][C:5]2[CH:8]=[C:9]([C:12]([F:15])([F:14])[F:13])[C:10]([OH:11])=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

3

반응물 2

HCID 7410AcetophenoneHCID 193891994-Hydroxy-3-methoxy-5-(trifluoromethyl)benzaldehyde

생성물 1

HCID 540570871-Phenyl-3-(3-methoxy-4-hydroxy-5-trifluoromethylphenyl)prop-2-en-1-one

실험 절차

The procedure described in Example 8 was repeated using 1.7 g of 3-methoxy-4-hydroxy-5-trifluoromethylbenzaldehyde and 1.0 g of acetophenone. Yield 1.1 g (45%), m.p. 166°-168° C.

출처 및 근거

ORD 기록
ord-bd8abb4cbe4b43b0b9131ebd70b8687c
출처 데이터셋
uspto-grants-1990_10
특허 번호
US04963590

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