Chloroacetyl chloride → 3,7-Bis(2-chloroacetamido)dibenzothiophene 5,5-dioxide

HRID 1089191

반응식

HRID 1089191 반응식
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]3[CH:10]=[CH:11][C:12]([NH2:14])=[CH:13][C:8]=3[S:7](=[O:16])(=[O:15])[C:6]=2[CH:17]=1.[Cl:18][CH2:19][C:20](Cl)=[O:21]>CC(C)=O>[Cl:18][CH2:19][C:20]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]3[CH:10]=[CH:11][C:12]([NH:14][C:20](=[O:21])[CH2:19][Cl:18])=[CH:13][C:8]=3[S:7](=[O:16])(=[O:15])[C:6]=2[CH:17]=1)=[O:21]

참가 물질

4

반응물 2

HCID 6577Chloroacetyl chlorideHCID 804123,7-Diaminodibenzothiophene-5,5-dioxide

생성물 1

HCID 221607093,7-Bis(2-chloroacetamido)dibenzothiophene 5,5-dioxide

시약·촉매·용매 1

HCID 180Acetone용매

반응 조건

온도
100 °C

실험 절차

A slurry of 21.8 g of 3,7-diaminodibenzothiophene S,S-dioxide in 400 ml of acetone was cooled in an ice bath while 30.2 ml of chloroacetyl chloride was carefully added. The bath was removed and the mixture heated at 100° C. with stirring, then cooled and poured into ice water. The precipitate was collected, washed with water and dried giving 34.9 g of the desired product as a solid.

후처리

  1. additionwas carefully added
  2. customThe bath was removed
  3. temperaturecooled
  4. additionpoured into ice water
  5. customThe precipitate was collected
  6. washwashed with water
  7. customdried

출처 및 근거

ORD 기록
ord-684a764440fd4ba3ac92f8a5407e739b
출처 데이터셋
uspto-grants-1990_10
특허 번호
US04965284

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