Thionyl Chloride → 3-(1-Methylfluoren-9-yl)propionyl Chloride

HRID 1089854노트

반응식

HRID 1089854 반응식
[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([OH:19])=O)[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1.O=S(Cl)[Cl:22]>>[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([Cl:22])=[O:19])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 150450953-(1-Methylfluoren-9-yl)propionic acid

생성물 1

HCID 150450963-(1-Methylfluoren-9-yl)propionyl Chloride

실험 절차

3-(1-Methylfluoren-9-yl)propionic acid (2.5 g, 9.9 mmol) was charged with SOCl2 (20 mL, in excess) at room temperature. The reaction mixture was boiled for 2 hr. Excess of thionyl chloride was removed under reduced pressure. The residual oil was used for the next step without further purification.

후처리

  1. customExcess of thionyl chloride was removed under reduced pressure
  2. customThe residual oil was used for the next step without further purification

출처 및 근거

ORD 기록
ord-f72077c274bc48209040beb6f717b564
출처 데이터셋
uspto-grants-1992_01
특허 번호
US05079260

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