Ethyl 1-(p-chlorobenzyl)-5-chloro-3-thiophenylindole-2-carboxylate → 1-(p Chlorobenzyl)-5-chloro-3-thiophenylindole-2-carboxylic acid

HRID 1090266

반응식

HRID 1090266 반응식
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([Cl:16])=[CH:13][CH:14]=3)[C:9]([C:17]3[S:18][CH:19]=[CH:20][CH:21]=3)=[C:8]2[C:22]([O:24]CC)=[O:23])=[CH:4][CH:3]=1>O1CCCC1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([Cl:16])=[CH:13][CH:14]=3)[C:9]([C:17]3[S:18][CH:19]=[CH:20][CH:21]=3)=[C:8]2[C:22]([OH:24])=[O:23])=[CH:27][CH:28]=1

참가 물질

3

반응물 1

HCID 67855865Ethyl 1-(p-chlorobenzyl)-5-chloro-3-thiophenylindole-2-carboxylate

생성물 1

HCID 232009311-(p Chlorobenzyl)-5-chloro-3-thiophenylindole-2-carboxylic acid

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Following the procedure of Preparation 6, but using ethyl 1-(p-chlorobenzyl)-5-chloro-3-thiophenylindole-2-carboxylate from Example 1 as the starting material and tetrahydrofuran as the solvent, the title compound was prepared, mp 185°-188° (dec.).

후처리

  1. customthe procedure of Preparation 6

출처 및 근거

ORD 기록
ord-a4d1ae8d5072407ab590cf9f4db69ff2
출처 데이터셋
uspto-grants-1992_01
특허 번호
US05081138

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