Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Silica → 5-(Benzyloxy)pentanal
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Silica | HCID 24261 | — |
| 반응물 | Magnesium orthosilicate | HCID 66225 | — |
| 반응물 | 5-(Benzyloxy)pentan-1-ol | HCID 221194 | — |
| 반응물 | HCID 178418287 | HCID 178418287 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 5-(Benzyloxy)pentanal | HCID 11063258 | 78.7% |
반응 단계
Under a nitrogen atmosphere a mixture of 8.0 grams (0.041 mole) of 7-phenyl-6-oxaheptan-1-ol and 1.4 grams of 95% silicon dioxide in 125 ml of methylene chloride was stirred, and 19.8 grams (0.090 mole) of pyridinium chlorochromate was added. Upon completion of addition, the reaction mixture was stirred at ambient temperature for four hours. After this time the reaction mixture was diluted with diethyl ether and then was passed through a column of magnesium silicate. The eluate was concentrated under reduced pressure yielding 6.2 grams of 7-phenyl-6-oxaheptan-1-al. The reaction was repeated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05081287 |
| 출처 데이터셋 | uspto-grants-1992_01 |
| ORD ID | ord-520dbc8b40a94caab5f42feba8bec5b3 |
| 출처 메모 | uspto-grants-1992_01 |