Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 1,3-Benzodioxole, 4,6-dimethyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3,5-Dimethylbenzene-1,2-diol | HCID 17737 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1,3-Benzodioxole, 4,6-dimethyl- | HCID 19913821 | 93% |
반응 단계
3,5-Dimethylcatechol (13.8 g) in a vigorously stirred mixture of dimethylsulphoxide (150 ml), dichloromethane (10 g) and sodium hydroxide (8.3 g) under nitrogen atmosphere was heated over an oil bath (120°-130° C.) for 2 hours. The mixture was poured into water (600 ml) and extracted (×4) with ether. The ethereal solution was dried and evaporated to afford 3,5-dimethyl-l,2-(methylenedioxy)benzene (14.0 g, 93%) as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05082848 |
| 출처 데이터셋 | uspto-grants-1992_01 |
| ORD ID | ord-f27c214ab15a42449914eb6809591599 |
| 출처 메모 | uspto-grants-1992_01 |