Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

HRID 1093015노트

반응식

HRID 1093015 반응식
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH2:11][C:12](=[O:14])[CH3:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].[Br:15]Br>O1CCOCC1>[Br:15][CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:2]([CH3:1])(=[O:3])=[O:4])[CH:6]=1)[C:12](=[O:14])[CH3:13]

참가 물질

4

반응물 2

HCID 24408BromineHCID 665884811-(3-(Methylsulfonyl)phenyl)propan-2-one

생성물 1

HCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.

후처리

  1. additionadded in two portions
  2. customThe solvent is removed in vacuo

출처 및 근거

ORD 기록
ord-7322d988ca48436db43a24f062528d8b
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08129541B2

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