Sodium Bicarbonate → HCID 59407750, 화합물

HRID 1093474노트

반응식

HRID 1093474 반응식
O.[C:2]1(C)[CH:7]=[CH:6][C:5]([S:8](O)(=O)=O)=[CH:4][CH:3]=1.[C:13](=[O:16])([O-])O.[Na+]>CO>[S:8]1[C:5]2[CH:6]=[CH:7][CH:2]=[CH:3][C:4]=2[C:2]([CH2:7][CH2:6][CH2:13][OH:16])=[CH:3]1

참가 물질

4

반응물 2

HCID 516892Sodium BicarbonateHCID 521998p-Toluenesulfonic acid monohydrate

생성물 1

HCID 59407750HCID 59407750, 화합물

시약·촉매·용매 1

HCID 887Methanol용매2회

실험 절차

A solution of compound 80-2 (2.04 g) and p-toluenesulfonic acid monohydrate (10.0 mg) in methanol (80 ml) was stirred at room temperature for 20 hr. Saturated aqueous sodium hydrogen carbonate was added to the reaction mixture, and methanol was evaporated under reduced pressure. Water was added to the obtained mixture, and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine and dried over anhydrous magnesium sulfate, and the solvent was concentrated under reduced pressure to give the object product (1.48 g) as a brown oil.

후처리

  1. customwas evaporated under reduced pressure
  2. additionWater was added to the obtained mixture
  3. extractionthe mixture was extracted with ethyl acetate
  4. washThe organic layer was washed with saturated brine
  5. dry with materialdried over anhydrous magnesium sulfate
  6. concentrationthe solvent was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-3922e066291a402cb23f29c3d600d8df
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08129361B2

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