2-Thiophenecarboxylic acid → 5-Butylthiophene-2-carboxylic acid

반응식

[CH2:1]([C:3]1[S:7][C:6]([C:8]([OH:10])=[O:9])=[CH:5][CH:4]=1)[CH3:2].S1C=C[CH:13]=[C:12]1C(O)=O.ICCCC>>[CH2:1]([C:3]1[S:7][C:6]([C:8]([OH:10])=[O:9])=[CH:5][CH:4]=1)[CH2:2][CH2:12][CH3:13]

참가 물질

반응물 3

HCID 107002-Thiophenecarboxylic acid

HCID 10962Butyl iodide

HCID 5881925-Ethylthiophene-2-carboxylic acid

생성물 1

HCID 123262235-Butylthiophene-2-carboxylic acid

실험 절차

The title compound is prepared in analogy to 5-ethyl-thiophene-2-carboxylic acid starting from 2-thiophenecarboxylic acid and 1-iodobutane; LC-MS: tR=0.92 min.

출처 및 근거

ORD 기록: ord-e8c4346ec62a4c0e9a26c9fe6585a306
출처 데이터셋: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08133910B2

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