5-(2-Methylpropyl)thiophene-2-carboxylic acid → 2-Ethyl-4-[5-(5-isobutyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol
반응식
[CH2:1]([C:5]1[S:9][C:8]([C:10]([OH:12])=O)=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].C([O:20][C:21]1[C:30]([CH3:31])=[CH:29][C:24]([C:25]([NH:27][NH2:28])=O)=[CH:23][C:22]=1[CH2:32][CH3:33])C1C=CC=CC=1>>[CH2:32]([C:22]1[CH:23]=[C:24]([C:25]2[O:12][C:10]([C:8]3[S:9][C:5]([CH2:1][CH:2]([CH3:3])[CH3:4])=[CH:6][CH:7]=3)=[N:28][N:27]=2)[CH:29]=[C:30]([CH3:31])[C:21]=1[OH:20])[CH3:33]참가 물질
3
실험 절차
2-Ethyl-4-[5-(5-isobutyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol is prepared in analogy to Example 29 from 5-isobutyl-thiophene-2-carboxylic acid and 4-benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide; LC-MS: tR=1.03 min, [M+1]+=343.22.
출처 및 근거
- ORD 기록
- ord-fb3a35b5aa024e2188f21d0b68f4c2a7
- 출처 데이터셋
- uspto-grants-2012_03