Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lithium hydroxide, monohydrate → 2-Aminoterephthalic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lithium hydroxide, monohydrate | HCID 168937 | — |
| 반응물 | 3-Amino-4-(methoxycarbonyl)benzoic acid | HCID 5235500 | — |
| 용매 | Methanol tetrahydrofuran water | HCID 21892291 | — |
| 생성물 | 2-Aminoterephthalic acid | HCID 2724822 | 63% |
반응 단계
3-Amino-4-(methoxylcarbonyl)benzoic acid (2.5 g, 12.8 mmol) was dissolved in a mixture of THF-MeOH—H2O (40 mL, 30:5:5) and then LiOH—H2O (2 g, 64 mmol) was added. The mixture stirred at RT over night. The reaction mixture was concentrated and the residue was dissolved in 5 mL of water and then acidified with 6N HCl to pH˜3. The solid was filtered and dried to give the desired product in 63% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08133998B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-43aae2f408c444f995f05a7c7bc98939 |
| 출처 메모 | uspto-grants-2012_03 |