Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 5-Fluoro-2-(tetrahydro-thiopyran-4-yloxy)benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 5-Fluorosalicylaldehyde | HCID 2737328 | — |
| 반응물 | 4-(Methanesulfonyl)oxytetrahydrothiopyran | HCID 12420265 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-Fluoro-2-(tetrahydro-thiopyran-4-yloxy)benzaldehyde | HCID 57743182 | — |
반응 단계
In a manner similar to the method described in Example 128a, 5-fluoro salicylaldehyde (Aldrich) reacted with methanesulfonic acid tetrahydro-thiopyran-4-yl ester prepared in Example 130a and potassium carbonate in dimethylformamide to give a solid. MS (H+), 241.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08134001B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-5d2bbcf707f34790b8e8bf82cddedefc |
| 출처 메모 | uspto-grants-2012_03 |