Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 5-(bromomethyl)pyrazine-2-carboxylate → 5-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenoxymethyl}-pyrazine-2-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 5-(bromomethyl)pyrazine-2-carboxylate | HCID 21973569 | — |
| 반응물 | 3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol | HCID 57421264 | — |
| 생성물 | 5-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenoxymethyl}-pyrazine-2-carboxylic acid methyl ester | HCID 59508579 | — |
반응 단계
The title compound was prepared in analogy to Example 101 from 3-chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol (obtained in Example 19, step 5) and 5-bromomethyl-pyrazine-2-carboxylic acid methyl ester [CAS Reg. No. 193966-70-0]. MS (m/e)=516.3 [MH+].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08138189B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-d5f8bc2308204ef7ba71ead52cf0981f |
| 출처 메모 | uspto-grants-2012_03 |