Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron tribromide → 5-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1,3-dimethyl-1H-pyridin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron tribromide | HCID 25134 | — |
| 반응물 | 5-[2-(2-chloro-4-methoxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1,3-dimethyl-1H-pyridin-2-one | HCID 66699498 | — |
| 생성물 | 5-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1,3-dimethyl-1H-pyridin-2-one | HCID 66699301 | — |
반응 단계
In analogy to Example 147, step 5, 5-[2-(2-chloro-4-methoxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1,3-dimethyl-1H-pyridin-2-one was reacted with BBr3 to give the title compound as a colorless solid. MS (m/e)=376.2 [M+H+].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08138189B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-256203201fef4414831958d80fe41e8c |
| 출처 메모 | uspto-grants-2012_03 |