N-(1-Ethyl-hexahydro-5-methyl-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide → n-(5-Ethyl-hexahydro-1-isopropyl-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide
반응식
C(N1C(=O)C(N[C:12](=[O:23])[C:13]2[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=2[F:22])(C)C(=O)NC1=O)C.[NH2:26][C:27]1([CH2:39][CH3:40])[C:32](=[O:33])[N:31]([CH:34]([CH3:36])[CH3:35])[C:30](=[O:37])[NH:29][C:28]1=[O:38]>>[CH2:39]([C:27]1([NH:26][C:12](=[O:23])[C:13]2[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=2[F:22])[C:32](=[O:33])[N:31]([CH:34]([CH3:36])[CH3:35])[C:30](=[O:37])[NH:29][C:28]1=[O:38])[CH3:40]참가 물질
3
실험 절차
Compound 20g was prepared by the same method described for 20f using 5-amino-5-ethyl-1-isopropylbarbituric acid (0.37 g, 2 mmol). The crude 5-ethyl-1-isopropyl-5-(tetrafluoro-benzamido)barbituric acid (20g) was obtained as white crystals and did not require further purification.
후처리
- customCompound 20g was prepared by the same method