7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine → (+/-)-2-[2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]propoxy]ethanol

HRID 1097337

반응식

HRID 1097337 반응식
Cl[C:2]1[C:3]2[S:20][C:19]([NH2:21])=[N:18][C:4]=2[N:5]=[C:6]([S:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=2[F:17])[N:7]=1.[NH2:22][CH:23]([CH3:29])[CH2:24][O:25][CH2:26][CH2:27][OH:28]>>[NH2:21][C:19]1[S:20][C:3]2[C:2]([NH:22][CH:23]([CH3:29])[CH2:24][O:25][CH2:26][CH2:27][OH:28])=[N:7][C:6]([S:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=3[F:17])=[N:5][C:4]=2[N:18]=1

참가 물질

3

실험 절차

Prepared by the method of example 2 step a), using the product of example 4, step b) and (+/−)-2-[2-aminopropoxy]ethanol,

후처리

  1. customPrepared by the method of example 2 step a),

출처 및 근거

ORD 기록
ord-4392fe7b63ca42a195aa64cdf228d696
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08143261B2

연결된 노트

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