4-Methoxybenzaldehyde → N-(4-Methoxybenzylidene)-N-(4-methoxybenzyl)amine

반응식

[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH2:8])=[CH:5][CH:4]=1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1>>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][N:8]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)=[CH:5][CH:4]=1

참가 물질

반응물 2

HCID 312444-Methoxybenzaldehyde

HCID 754524-Methoxybenzylamine

생성물 1

HCID 578709N-(4-Methoxybenzylidene)-N-(4-methoxybenzyl)amine수율 131%

실험 절차

4-Methoxybenzylamine (40 g, 290 mmol) was cooled to 0° C., and p-anisaldehyde (39.7 g, 292 mmol) was added dropwise. The reaction was stirred at ambient temperature for two hours, concentrated under reduced pressure, and further dried under high vacuum overnight to provide 97 g of N-(4-methoxybenzyl)-N-[(4-methoxyphenyl)methylidene]amine as a white, waxy solid.

후처리

concentrationconcentrated under reduced pressure
customfurther dried under high vacuum overnight

출처 및 근거

ORD 기록: ord-b566f8d0d4604980b48691a32407a87c
출처 데이터셋: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08143270B2

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