Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3,6-Trifluorobenzaldehyde → [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3,6-Trifluorobenzaldehyde | HCID 517845 | — |
| 반응물 | 5-(Pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine | HCID 51358551 | — |
| 반응물 | 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine | HCID 58086899 | — |
| 생성물 | [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone | HCID 58086752 | — |
반응 단계
was prepared using the protocol of Steps 3 and 4 of Scheme 17, substituting propane-2-sulfonic acid (2,4-difluoro-3-formyl-phenyl)-amide with 2,3,6-Trifluoro-benzaldehyde and 5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine 89 with 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine in Step 3. MS (ESI) [M−H+]−=429.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08143271B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-e9f1e377b6f74de8a46373c27c522164 |
| 출처 메모 | uspto-grants-2012_03 |