Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitrosobenzene → N-hydroxy-N-phenylcyclopropanecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitrosobenzene | HCID 11473 | — |
| 반응물 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 반응물 | Cyclopropanecarboxaldehyde | HCID 123114 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-hydroxy-N-phenylcyclopropanecarboxamide | HCID 24938705 | — |
반응 단계
DBU (15 mg, 0.1 mmol) was added under argon to a solution of cyclopropanal (70 mg, 1 mmol), nitrosobenzene (107 mg, 1 mmol) and catalyst (36.4 mg, 0.1 mmol) in dichloromethane (5 mL). The reaction mixture was stirred at room temperature for 10 min. The solvent was removed under vacuum, and the residue was purified by flash silica gel column chromatography using hexane and ethyl acetate as the eluents.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08143423B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-9adaf506175c49d68e38d70446ff1402 |
| 출처 메모 | uspto-grants-2012_03 |