Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2-Fluorophenyl)ethan-1-ol → N-{4-[2-(2-Fluorophenyl)ethoxy]benzoyl}glycine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2-Fluorophenyl)ethan-1-ol | HCID 2733296 | — |
| 반응물 | N-(4-Hydroxybenzoyl)glycine tert-butyl ester | HCID 10682169 | — |
| 생성물 | N-{4-[2-(2-Fluorophenyl)ethoxy]benzoyl}glycine | HCID 66811873 | 73.4% |
반응 단계
The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (231 mg, 0.919 mmol) prepared in Example 1 (1a) and 2-(2-fluorophenyl)ethanol (137 μL, 1.02 mmol) to give 214 mg of the title compound (white powder, yield: 73%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08143446B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-4bdd2ac5751b4515867509b9b42b8031 |
| 출처 메모 | uspto-grants-2012_03 |