4,6-Dimethoxysalicylaldehyde → 3-(4-methoxy-3-nitrobenzylsulfonyl)-5,7-dimethoxy-2H-chromen-2-one

HRID 1099724

반응식

HRID 1099724 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5](O)[C:6](=[C:9]([O:11][CH3:12])[CH:10]=1)[CH:7]=O.[CH3:14][O:15][C:16]1[CH:29]=[CH:28][C:19]([CH2:20][S:21]([CH2:24][C:25]([OH:27])=[O:26])(=[O:23])=[O:22])=[CH:18][C:17]=1[N+:30]([O-:32])=[O:31]>C(O)(=O)C>[CH3:14][O:15][C:16]1[CH:29]=[CH:28][C:19]([CH2:20][S:21]([C:24]2[C:25](=[O:27])[O:26][C:5]3[C:6]([CH:7]=2)=[C:9]([O:11][CH3:12])[CH:10]=[C:3]([O:2][CH3:1])[CH:4]=3)(=[O:22])=[O:23])=[CH:18][C:17]=1[N+:30]([O-:32])=[O:31]

참가 물질

4

반응물 2

HCID 697254,6-DimethoxysalicylaldehydeHCID 404270672-((4-Methoxy-3-nitrobenzyl)sulfonyl)acetic acid

생성물 1

HCID 116262353-(4-methoxy-3-nitrobenzylsulfonyl)-5,7-dimethoxy-2H-chromen-2-one수율 47%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of 4,6-dimethoxysalicylaldehyde (1 mmol) and 2-(4-methoxy-3-nitrobenzylsulfonyl)acetic acid (1 mmol) in acetic acid (10 mL) was subjected to the General Procedure 2, Method A to generate a 47% yield of the title compound; m.p. 224-225° C.

출처 및 근거

ORD 기록
ord-ea3eb5212b6d4a11a6efa07b9510b8c7
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08143428B2

연결된 노트

불러오는 중…