Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Maleimide → tetrahydropyrrolo[3,4-c]carbazole-1,3(2H, 3aH)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Maleimide | HCID 10935 | — |
| 반응물 | 2-{2-[2-(2-Chlorophenyl)ethenyl]-5-methoxy-1H-indol-1-yl}ethanol | HCID 73857732 | — |
| 생성물 | tetrahydropyrrolo[3,4-c]carbazole-1,3(2H, 3aH)-dione | HCID 131725903 | 79% |
반응 단계
Reaction of 2-{2-[2-(2-Chlorophenyl)ethenyl]-5-methoxy-1H-indol-1-yl}ethanol (III; Ar=2-chlorophenyl, R10═CH2CH2OH) (44) prepared according to example 41 with maleimide according to the procedure described in example 68 gave 4-(2-Chlorophenyl)-6-(2-hydroxyethyl)-9-methoxy-4,5,6,1 Oc-tetrahydropyrrolo[3,4-c]carbazole-1,3(2H, 3aH)-dione (IV; Ar=2-chlorophenyl, R10═CH2CH2OH) (45) in a 79% yield as an oily solid, which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094798B1 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-7c0e1b6db3f34a84be1395fb66bcc132 |
| 출처 메모 | uspto-grants-2006_08 |