3-Bromo-4-methylpyridine → N-(5-(Cyclopropylcarbamoyl)-2-methylphenyl)-5-(4-methylpyridin-3-yl)thiophene-2-carboxamide

반응식

[Br:25][c:26]1[cH:27][n:28][cH:29][cH:30][c:31]1[CH3:32].[CH:1]1([NH:4][C:5](=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH3:24])[c:11]([NH:13][C:14](=[O:15])[c:16]3[cH:17][cH:18][c:19]([B:21]([OH:22])[OH:23])[s:20]3)[cH:12]2)[CH2:2][CH2:3]1>>[CH:1]1([NH:4][C:5](=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH3:24])[c:11]([NH:13][C:14](=[O:15])[c:16]3[cH:17][cH:18][c:19](-[c:26]4[cH:27][n:28][cH:29][cH:30][c:31]4[CH3:32])[s:20]3)[cH:12]2)[CH2:2][CH2:3]1

참가 물질

반응물 2

HCID 8176303-Bromo-4-methylpyridine

HCID 597615035-(5-(Cyclopropylcarbamoyl)-2-methylphenylcarbamoyl)thiophen-2-ylboronic acid

생성물 1

HCID 59761479N-(5-(Cyclopropylcarbamoyl)-2-methylphenyl)-5-(4-methylpyridin-3-yl)thiophene-2-carboxamide

출처 및 근거

ORD 기록: ord-5c433841ef414edb9a9b7566e9325c00
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…