HCID 178493728, 화합물 → HCID 178512636, 화합물
반응식
[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]2[C:18](=[O:19])[C:17](=[O:20])[C:16]=2OC)[N:9]=1)[C:2]([NH2:4])=[NH:3]>CO>[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:16]2[C:17](=[O:20])[C:18](=[O:19])[C:15]=2[NH:14][CH2:13][CH2:12][CH2:11][CH2:10][C:8]2[N:9]=[C:5]([NH:1][C:2]([NH2:4])=[NH:3])[S:6][CH:7]=2)[N:9]=1)[C:2]([NH2:4])=[NH:3]참가 물질
3
실험 절차
A mixture of 2-quanidino-4-(4-aminobutyl)thiazole (0.105 g) and 1-[4-(2-guanidinothiazol-4-yl)butylamino]-2-methoxycyclobutene-3,4-dione (0.16 g) in dry methanol (5 ml) was stirred for 18 hours at room temperature. The white solid was filtered off, washed with methanol and dried in vacuo to give 1,2-bis[4-(2-guanidinothiazol-4-yl)-butylamino]cyclobutene-3,4-dione, 0.16 g., m.p. 228°-229° C.
후처리
- filtrationThe white solid was filtered off
- washwashed with methanol
- customdried in vacuo