Triethylamine → HCID 178512637, 화합물

반응식

Cl.Cl.[NH:3]([C:7]1[S:8][CH:9]=[C:10]([CH2:12][S:13][CH2:14][CH2:15][NH2:16])[N:11]=1)[C:4]([NH2:6])=[NH:5].[NH:17]([C:21]1[S:22][CH:23]=[C:24]([CH2:26][CH2:27][CH2:28][CH2:29][NH:30][C:31]2[C:34](=O)[C:33](=[O:36])[C:32]=2[O:37]C)[N:25]=1)[C:18]([NH2:20])=[NH:19].C(N(CC)CC)C>CO>[NH:3]([C:7]1[S:8][CH:9]=[C:10]([CH2:12][S:13][CH2:14][CH2:15][NH:16][C:34]2[C:33](=[O:36])[C:32](=[O:37])[C:31]=2[NH:30][CH2:29][CH2:28][CH2:27][CH2:26][C:24]2[N:25]=[C:21]([NH:17][C:18]([NH2:20])=[NH:19])[S:22][CH:23]=2)[N:11]=1)[C:4]([NH2:6])=[NH:5]

참가 물질

실험 절차

A mixture of 2-guanidino-4-[(2-aminoethyl)-thiomethyl]thiazole dihydrochloride (0.024 g), 1-[4-(2-guanidinothiazol-4-yl)butylamino]-2-methoxycyclobutene-3,4-dione (0.032 g) and triethylamine (0.03 ml) in dry methanol (1 ml) was stirred for 18 hours at room temperature. The white solid was filtered off, washed with methanol and dried in vacuo to give 1-[2-(2-guanidinothiazol-4-ylmethylthio)ethylamino]-2-[4-(2-guanidinothiazol-4-yl)butylamino]cyclobuten-3,4-dione, (0.022 g), m.p. 208°-210°.