3-(Nitro-n-butylamino)benzophenone → HCID 54315355, 화합물

HRID 1105839노트

반응식

HRID 1105839 반응식
[N+]([N:4](CCCC)[C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][CH:18]=1)[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9])([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:4][C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][C:18]=1[NH:4][CH2:5][CH2:18][CH2:17][CH3:16])[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9]

참가 물질

5

반응물 2

HCID 205552293-(Nitro-n-butylamino)benzophenoneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 54315355HCID 54315355, 화합물수율 88.6%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution of 3-(nitro-4-n-butylamino)-benzophenone (5.96 g.; 0.02 mole) in ethanol (200 ml.) is added palladium on charcoal (5%; 0.1 g.). The mixture is hydrogenated until theoretical uptake of hydrogen has occurred (about three hours) and then let stand at room temperature overnight. The reaction mixture is filtered to remove the catalyst and the filtrate concentrated under vacuum to afford 4.75 g. (88.6% yield) of 3-amino-4-n-butylaminobenzophenone.

후처리

  1. custom(about three hours)
  2. filtrationThe reaction mixture is filtered
  3. customto remove the catalyst
  4. concentrationthe filtrate concentrated under vacuum
  5. customto afford 4.75 g

출처 및 근거

ORD 기록
ord-36486451a3814c69a32801938eb84ea6
출처 데이터셋
uspto-grants-1982_01
특허 번호
US04310537

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