2,6-Dimethylbenzoic acid → 3-(Chlorosulfonyl)-2,6-dimethylbenzoic acid
반응식
[Cl:1][S:2]([OH:5])(=O)=[O:3].[CH3:6][C:7]1[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[C:8]=1[C:9]([OH:11])=[O:10]>O>[CH3:6][C:7]1[C:15]([S:2]([Cl:1])(=[O:5])=[O:3])=[CH:14][CH:13]=[C:12]([CH3:16])[C:8]=1[C:9]([OH:11])=[O:10]참가 물질
4
반응 조건
- 온도
- 55 °C
실험 절차
4 ml of chlorosulfonic acid are added slowly to 1 g (0.067 mol) of 2,6-dimethylbenzoic acid and the reaction mixture is stirred for 1 hour at 55° C. After cooling, the mixture is poured into 100 ml of iced water. The precipitate formed is filtered off, washed with cold water and then dried in a desiccator under vacuum to give 1.22 g of the expected product in the form of a white solid (yield=73%).
후처리
- temperatureAfter cooling
- customThe precipitate formed
- filtrationis filtered off
- washwashed with cold water
- customdried in a desiccator under vacuum
출처 및 근거
- ORD 기록
- ord-c916df01ab0a4736a6e5e0b5b8525a9b
- 출처 데이터셋
- uspto-grants-2000_05
- 특허 번호
- US06063791
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