참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 1,2-Epoxyoctadecane | HCID 23872 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-(2-Hydroxyethylamino)-2-octadecanol | HCID 18332285 | 74.6% |
반응 단계
A 300-ml flask equipped with a stirrer and a dropping funnel was charged with 45.8 g (0.75 mol) of ethanolamine and 9 g of ethanol. While stirring the mixture at 80° C., 13.4 g (50 mmol) of 1,2-epoxyoctadecane were added dropwise over 2 hours. Water was added to the resultant reaction mixture, and white crystals formed were collected by filtration, washed with water and then recrystallized from methanol, thereby obtaining 12.3 g (yield: 74.6%) of the title compound (IIc-1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05723497 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-80c2effe4d3141839b36b2e47237d5ac |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
