Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 2-(2-Acetoxyethyl)thio-2',4'-difluoroacetophenone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Ethanol, 2-mercapto-, 1-acetate | HCID 98505 | — |
| 반응물 | 2-Chloro-1-(2,4-difluorophenyl)ethanone | HCID 588083 | — |
| 생성물 | 2-(2-Acetoxyethyl)thio-2',4'-difluoroacetophenone | HCID 10659915 | 65.6% |
반응 단계
Using 2-chloro-2',4'-difluoroacetophenone (2.0 g, 0.010 mol), 2-acetoxyethanethiol (J. Chem. Soc., 1952, 817.) (1.5 g, 0.013 mol), potassium carbonate (1.8 g, 0.013 mol) and methanol (50 mol), 2-(2-acetoxyethyl)thio-2',4'-difluoroacetophenone (1.8 g, yield: 62.0%) was obtained as a colorless oil by similar procedures to Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06063945 |
| 출처 데이터셋 | uspto-grants-2000_05 |
| ORD ID | ord-52f2747fa930491da19a9c6a8a70828a |
| 출처 메모 | uspto-grants-2000_05 |