Isopropylamine → HCID 690424, 화합물

반응식

[N+](C1C=C[C:7]([C:8](Cl)=[O:9])=CC=1)([O-])=O.C(N)(C)C.[CH:17]([NH:20][C:21](=[O:31])[C:22]1[CH:27]=[CH:26][C:25]([N+:28]([O-])=O)=[CH:24][CH:23]=1)([CH3:19])[CH3:18]>>[CH:17]([NH:20][C:21](=[O:31])[C:22]1[CH:27]=[CH:26][C:25]([NH:28][C:8](=[O:9])[CH3:7])=[CH:24][CH:23]=1)([CH3:19])[CH3:18]

참가 물질

반응물 3

HCID 6363Isopropylamine

HCID 85024-Nitrobenzoyl chloride

HCID 347926N-Isopropyl-4-nitrobenzamide

생성물 1

HCID 690424HCID 690424, 화합물

실험 절차

The method of Example 3 is repeated using 4-nitrobenzoyl chloride and iso-propyl amine in the amidation step. This yields N-iso-propyl-4-nitrobenzamide (CPI1026).

출처 및 근거

ORD 기록: ord-0d4cf20e74944a43a1e750159147aae1
출처 데이터셋: uspto-grants-2000_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06066765

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