Hypochlorous Acid → N-chloro-2-ethylhexyl carboxamide

HRID 1109267

반응식

HRID 1109267 반응식
[CH2:1]([CH:3]([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:4][C:5]([NH2:7])=[O:6])[CH3:2].[Cl:12]O>C(OCC)(=O)C>[Cl:12][NH:7][C:5]([CH2:4][CH:3]([CH2:1][CH3:2])[CH2:8][CH2:9][CH2:10][CH3:11])=[O:6]

참가 물질

4

반응물 2

HCID 24341Hypochlorous AcidHCID 126142952-Ethylhexyl carboxamide

생성물 1

HCID 19022272N-chloro-2-ethylhexyl carboxamide수율 98%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

2-ethylhexyl carboxamide (35.75 g, 250 mmol) was suspended in 300 ml of ethyl acetate and cooled to 1°. Hypochlorous acid (43.3 g of 30.6% solution, 252 m mol) was added dropwise over 13 minutes with stirring. After 10 minutes, the cooling bath was removed and stirring continued for 1 hour while the mixture warmed to room temperature. The ethyl acetate layer was then separated and dried (MgSO4) and the solvent was removed on the rotary evaporator and, finally, on the vacuum pump to give 44 g (98%) of colorless liquid N-chloro-2-ethylhexyl carboxamide.

후처리

  1. temperaturecooled to 1°
  2. customthe cooling bath was removed
  3. stirringstirring
  4. waitcontinued for 1 hour while the mixture
  5. customThe ethyl acetate layer was then separated
  6. dry with materialdried (MgSO4)
  7. customthe solvent was removed on the rotary evaporator

출처 및 근거

ORD 기록
ord-375172837e9046319c78f51387520bbe
출처 데이터셋
uspto-grants-1994_06
특허 번호
US05319133

연결된 노트

불러오는 중…