참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | 2,2-Dimethylvaleroyl chloride | HCID 519171 | — |
| 생성물 | 2,2-Dimethylpentanamide | HCID 83180 | 86% |
반응 단계
Ammonium hydroxide (250 ml) was stirred and cooled to 1° C. and 2,2-dimethyl valeroyl chloride (49.7 g, 95%, 318 mmol) was added dropwise over 30 minutes. After stirring at room temperature for an additional 1/2 hour, the white solid product was recovered by filtration, washed with water and allowed to air dry to give 35.4 g (86%) of the desired amide, mp 94°-95° (lit. mp 95°-96° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05319133 |
|---|
| 출처 데이터셋 | uspto-grants-1994_06 |
|---|
| ORD ID | ord-3a9e20c6bbea417cae8668dd93d16f00 |
|---|
| 출처 메모 | uspto-grants-1994_06 |
|---|
