돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1109276생성일: 2026년 10월 27일

Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

https://huagongshe.com/reaction/1109276

반응식

참여 물질

역할이름HCID투입량
반응물FormaldehydeHCID 712—
반응물Dimethyl fluoromalonateHCID 2737111—
생성물Dimethyl alpha-hydroxymethyl-alpha-fluoromalonateHCID 10910147—

반응 단계

The process according to the invention for preparing an α-fluoroacrylic acid ester is carried out in three stages. First dimethyl α-fluoromalonate is reacted with formaldehyde to give dimethyl a-hydroxymethyl-α-fluoromalonate, which is then hydrolyzed and the hydrolysis product is dicarboxylated and dehydrated, and finally the resulting α-fluoroacrylic acid is esterified with an alcohol of the formula (3).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05319131
출처 데이터셋uspto-grants-1994_06
ORD IDord-fca26e6d78084861ac2ddc1bf309c09d
출처 메모uspto-grants-1994_06